Yacht Life Sciences has a vacancy for a Senior or Principal Scientist Upstream Processing (USP) at Janssen Vaccines in Leiden.

The USP department is responsible for early- as well as late-stage development of scalable, pharmaceutical-grade production processes for viral vaccines using mammalian cell lines as a production platform. Novel technologies are used to make sure that the processes are safe, reliable, scalable and cost-effective, so that the vaccines can be produced in large quantities at low costs. The developed production processes are transferred into GMP production facilities for the production of clinical batches and scaled-up for commercial production. This is done in close collaboration with many partners in Discovery, Development and Supply Chain in an international environment.

Within the USP department, a lab team is responsible for performing all hands-on experimental activities, data processing and documentation, whereas a team of Scientists is responsible for the overall scientific approach and progress within their projects. The current focus of the USP department is on developing robust processes for the manufacturing of the COVID-19 and RSV vaccines and transferring the technology to multiple production facilities. In order to support these activities, we are looking for an experienced Senior or Principal Scientist USP.

Responsibilities: 

• Leads teams of motivated process developers
• Develops and executes USP early- and late-stage development and tech transfer strategies
• Creates and manages research plans with greater complexity in the delivery of business results
• Represents USP in multidisciplinary project team(s)
• Acts as senior author in the preparation of presentations, technical reports, documents for regulatory filing and patents
• Applies the latest technological innovations into the daily work. One of the major innovations currently explored is modeling, data science and statistical analysis applied to bioprocessing